Intranasal Hydromorphone
 Partners in Care has prepared several different opioid (Hydromorphone and Morphine) nasal sprays in various strengths to abort acute migraine pain.  For break through pain in palliative care, the nasal morning dosing provides fast acting non invasive dosage form. The patients and their physicians have found these preparations to fast acting and very effective.
      
 Pharmacokinetics and bioavailability of single-dose intranasal hydromorphone hydrochloride in healthy volunteers.

A multiple-dose phase I study of intranasal hydromorphone hydrochloride in healthy volunteers.